Acido ribonucleic
Acido ribonucleic (ARN o RNA) es un acido nucleic. Isto significa que ille consiste de un catena longe de unitates de nucleotide. Un nucleotide consiste de un basse nitrogenous nominate nucleobasse, un saccharo/sucre de ribose, e un phosphate. ARN es multo similarte con le ADN, ma ha differencias in alicun/pauc importante detailes de structura: in le cellula, ARN es monocatenari (consiste de un filo), durante que ADN es bicatenari; ARN nucleotides contine ribose durante que ADN contine deoxyribose (un typo de ribose ommite uno atomo de oxygeno); e ARN ha le base de uracil e non de thymine que es presente in ADN.
| Acido ribonucleic |
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| instantia de: structural class of chemical entities[*] |
| subclasse de: nucleic acids[*], biopolymer[*], gene product[*], polyribonucleotide[*] |
| parte de: RNA binding[*], RNA catabolic process[*], RNA metabolic process[*], RNA phosphodiester bond hydrolysis[*], RNA transport[*], RNA transmembrane transporter activity[*], protein-DNA-RNA complex[*], ribosoma, ribonucleoprotein granule[*], protein-lipid-RNA complex[*], HDL-containing protein-lipid-RNA complex[*], LDL-containing protein-lipid-RNA complex[*], ribonucleoprotein complex[*], RNA import into nucleus[*], RNA export from nucleus[*], RNA import into mitochondrion[*], gene silencing[*], RNA biosynthetic process[*], ATP-dependent activity, acting on RNA[*], catalytic activity, acting on RNA[*] |
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| Commons: RNA |
Structura
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Cate nucleotide in ARN contine un saccharo/sucre de ribose, con carbones numerotate 1' a 5'. Le bases pote formar ligamines de hydrogeno inter cytosine e guanine, inter adenine e uracil e inter guanine e uracil. ligamines de hydrogeno[1] Altere interactiones es possibile[2]
Comparition con ADN
modificarARN e ADN e differite in 3 characteristicas principal.
Typos de ARN
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Historia de discoperta
modificarLe acidos nucleic esseva discoperta in 1868 de Friedrich Miescher, que nominate le material 'nuclein' proque ille esseva trovate in le nucleus.[4] Le cellules prokaryotic que non ha un nucleus, contine acidos nucleic, es un discoperta tarde. Le role de ARN in le synthese del protein esseva suspectate in 1939.[5] Severo Ochoa ha ganiate le Premio Nobel in medicina in 1959 dupo illo ha discoperta como ARN es synthesite.[6]
Vide etiam
modificarReferentias
modificar- ↑ "Diversity of base-pair conformations and their occurrence in rRNA structure and RNA structural motifs" (December 2004). Journal of Molecular Biology 344 (5): 1225–49. doi:. PMID 15561141.
- ↑ Barciszewski J, Frederic B, Clark C (1999). RNA biochemistry and biotechnology. Springer, 73–87. ISBN 0792358627. OCLC 52403776.
- ↑ Tan ZJ, Chen SJ (2008). "Salt dependence of nucleic acid hairpin stability". Biophys. J. 95: 738–52. doi:. PMID 18424500.
- ↑ Dahm R (2005). "Friedrich Miescher and the discovery of DNA". Developmental Biology 278 (2): 274–88. doi:. PMID 15680349.
- ↑ Caspersson T, Schultz J (1939). "Pentose nucleotides in the cytoplasm of growing tissues". Nature 143: 602–3. doi:.
- ↑ Ochoa S (1959). Enzymatic synthesis of ribonucleic acid. Nobel Lecture.
Ligamines externe
modificar- RNA World website Archived 2007-03-14 at the Wayback Machine Collection de ligamines (structures, sequences, utiles, journals)
- Nucleic Acid Database Archived 2007-10-12 at the Wayback Machine Imagines de ADN, ARN e complexes.