Human papillomavirus

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Human papillomavirus (HPV) (accurtamento pro virus del papilloma human) es un virus del familia Papillomaviridae qui es pathogene in humanes. Son contagiose inter humanes per contact del pelle o mucosas. Pote se manifestar per condylomas (verrucas).

Wikipedia:Uso de taxobox

Human papillomavirus

Classification scientific

Dominio:	Monodnaviria
Regno:	Shotokuvirae
Phylo:	Cossaviricota
Classe:	Papovaviricetes
Ordine:	Zurhausenvirales
Familia:	Papillomaviridae
Subfamilia:	Firstpapillomavirinae

Generes
de "Human papillomaviros":

Alphapapillomavirus^[1]^[2]
- αPV 1 (HPV-32 et 42)
- αPV 2 (HPV-3, 10, 28, 29, 77, 78, 94, 117, 125, 160)
- αPV 3 (HPV-61, 62, 72, 81, 83, 84, 86, 87, 89, 102 et 114)
- αPV 4 (HPV-2, 27 et 57)
- αPV 5 (HPV-26, 51, 69 et 82)
- αPV 6 (HPV-30, 53, 56 et 66)
- αPV 7 (HPV-18, 39, 45, 59, 68, 70, 85 et 97)
- αPV 8 (HPV-7, 40, 43 et 91)
- αPV 9 (HPV-16, 31, 33, 35, 52, 58 et 67)
- αPV 10 (HPV-6, 11, 13, 44 et 74)
- αPV 11 (HPV-34 et 73)
- αPV 13 (HPV-54)
- αPV 14 (HPV-71, 90 et 106)
Betapapillomavirus
- βPV 1 (HPV-5)
- βPV 2 (HPV-9)
- βPV 3 (HPV-49)
- βPV 4 (HPV-cand92)
- βPV 5 (HPV-cand96)
Gammapapillomavirus
- γPV 1 (HPV-4)
- γPV 2 (HPV-48)
- γPV 3 (HPV-50)
- γPV 4 (HPV-60)
- γPV 5 (HPV-88)
Mupapillomavirus
- μPV 1 (HPV-1)
- μPV 2 (HPV-63)
Nupapillomavirus
- νPV 1 (HPV-41)

Se estima que de 70 % ad 80 % del adultos in copulo sera infectate per un papillomavirus^[3]^[4]. Le majoritate del casos es asymptomatic ma alcun cippos son cancerogene (principalmente HPV-16, -18, -31 e -33). Papillomaviros son implicate in plus que 90 % del canceres del cervice uterin^[5] ma alsi altere canceres como le cancere del gula (gorga).

Es importante vaccinar le preadolescentes (pueras e pueros, typicamente inter 9 e 14 annos) contra papillomaviros cancerogene pro proteger les de futur canceres.^[6]

Classification

Se denombra plus de 200 genotypos differente de papillomaviros cuje 120 potente infectar humanes.^[3] Iste ultimes appartine a differente generes identificate per un character grec: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus e Nupapillomavirus.^[7]

Per exemplo:

αPV 5: HPV-51, -82, etc.
αPV 6: HPV-56, etc.
αPV 7: HPV-18, -39, -45, -59, -68, etc.
αPV 9: HPV-16, -31, -33, -35, -52, -58, etc.
αPV 11: HPV-73, etc.

Pathogenicitate

Cippos HPV-16, -18, -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -68, -73 e -82 pote generar precancerose lesiones. HPV-6 e 11, inter alteres, son responsabile de condyloma acuminate o verruca genital.^[8]

De plus, le HPV-5 pote generar pelle carcinomas in patientes affectate de epidermodysplasia verruciforme (EV).^[9]

Prevention

Hodie, existe un vaccino protegente contra le cippos le plus pathogene: HPV-6, -11, -16, -18, -31, -33, -45, -52 e -58.^[10]

Juvenes debe esser vaccinate ante lor prime contamination (typicamente inter 9 e 14 annos).^[6]

Referentias

[1] [https://ictv.global/report/chapter/papillomaviridae/papillomaviridae/alphapapillomavirus Subfamily: Firstpapillomavirinae Genus: Alphapapillomavirus]. ictv.global..

[2] ttps://ictv.global/ictv/proposals/2010.001a-kkkV.A.v2.Papillomaviridae.pdf

[SPF-3] 3,0 ^3,1 https://www.santepubliquefrance.fr/maladies-et-traumatismes/maladies-a-prevention-vaccinale/infections-a-papillomavirus/la-maladie/#tabs

[4] ttps://www.liberation.fr/societe/sante/papillomavirus-un-tiers-des-hommes-de-plus-de-quinze-ans-sont-porteurs-dans-le-monde-20230817_BKWXSADWOBGLDHZORKSVBPNJ54/

[5] :10.3389/fpubh.2020.552028

[OMS-6] 6,0 ^6,1 https://www.who.int/news-room/fact-sheets/detail/human-papilloma-virus-and-cancer

[7] ttps://ictv.global/taxonomy

[8] ttps://depistage.be/ist/hpv/

[9] :10.1051/medsci/2008245454

[10] ttps://www.mesvaccins.net/web/vaccines/523-gardasil-9

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